A Famous Pair of Egyptian Twins

Pair of Dizygous Twins of Consanguineous Parents*

The classical form of amyotrophic lateral sclerosis (ALS) or Charcot's disease contains both familial and sporadic cases. The familial form has been extensively reviewed by Faveret (1959), Haberlandt (1964), and Becker (1966). Sporadic cases present the same clinical features. In addition, there is a form of the disease encountered in the native inhabitants of Guam and Japan. It displays severa...

Iris mammillations in a pair of twins with Cowden syndrome

CS: Cowden syndrome PTEN: phosphatase and tensin homolog INTRODUCTION Iris mammillation is an uncommon congenital anomaly of the eye that is rarely reported in the literature; initial reports describe iris mammillations using different terminology, such as bilateral iris melanosis, dotted Swiss iris, and bilateral diffuse iris nodular nevi. Microscopic examination finds focal nesting of spindle...

Cerebellar asymmetry in a pair of monozygotic handedness-discordant twins.

Increasing evidence for a cerebellar role in human cognition has accrued with respect to anatomically and functionally distinct lobules. Questions of laterality, however, have been largely overlooked. This study therefore introduced and applied a novel measurement protocol for comparatively bias-free analysis of cerebellar asymmetries. Volumetric measurements were performed on magnetic resonanc...

Double 'suicide' by chloroform in a pair of twins.

Xanthoma Disseminatum In a Pair of Blind, Deaf Male Twins

Xanthoma disseminatum (XD) is a rare normolipemic histiocytic disorder of non-Langerhans cell origin characterized by erythematous to tan/brown papules in flexor surfaces. Considered a generally benign, chronic disease of unknown etiology, XD typically affects the skin, mucous membranes, and less commonly, other organs. To date, there has been no typical or consistent inheritance pattern descri...